MatSciCon2023 Starch 3D printing for the creation of individualised medication
The "Materials+Technologies" (GMT) Group at UPV/EHU has employed 3D printing to create tablets based on several types of starch for the aim of individualised therapy, and they have confirmed that medication release can be adjusted by selecting the proper starch type and tablet shape.
Traditional procedures often fail to address the unique demands of patients while still producing medications with particular criteria. In reality, because traditional medications frequently follow adult dosage guidelines, paediatric and elderly patients need doses that are appropriate for their age. Additionally, many patient populations require particular dosage form substitutes to make it easier to administer medications orally. Rapidly dissolving pills are becoming a popular choice in this regard because they start to dissolve as soon as they are placed on the tongue. Controlled drug release over time is another issue that pharmaceutical companies must deal with, particularly when the drug is hydrophobic, meaning that it is difficult to dissolve in water.
According to Kizkitza González of the UPV/Materials+Technologies EHU's Group, "3D printing technology is an advanced approach for personalised medicine and the production of on-demand drug-release tablets" in this context (GMT). The primary objective of this research was to create 3D printed starch-based tablets for the specialised delivery of hydrophobic medications, according to the paper's author.
In 3D printing, materials are deposited in accordance with the digital model created by computer design software, allowing for the layer-by-layer manufacturing of objects. "We were able to prepare tablets based on three types of starch - two types of maize starch (normal and waxy) and one type of potato starch- with different geometries and loaded with a non-soluble drug," said Kizkitza González. This was accomplished using a quick, straightforward methodology and 3D printing.
Potato with corn starch
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